Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15694788 | 0.85 | HTT (0.55) | POLBHTTLMNANPSR1CYP1A2 | |
| SCHEMBL19441408 | 0.84 | CYP1A2 (0.49) | POLBLMNANPSR1CYP1A2CYP2C19 | |
| SCHEMBL17067820 | 0.82 | CYP1A2 (0.67) | POLBLMNANPSR1CYP1A2CYP2C19 | |
| SCHEMBL15694787 | 0.81 | ALDH1A1 (0.56) | HTTLMNANPSR1CYP1A2CYP2C19 | |
| SCHEMBL19441409 | 0.80 | MAPT (0.47) | LMNACYP1A2CYP2C19MAPTALDH1A1 | |
| SCHEMBL8645438 | 0.79 | MAPT (0.50) | LMNANPSR1CYP1A2CYP2C19MAPT | |
| SCHEMBL4555171 | 0.78 | CYP1A2 (0.62) | POLBLMNANPSR1CYP1A2CYP2C19 | |
| SCHEMBL19449699 | 0.78 | CYP1A2 (0.57) | POLBLMNANPSR1CYP1A2CYP2C19 | |
| SCHEMBL10904748 | 0.76 | CYP1A2 (0.68) | POLBLMNANPSR1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL17560953 | 0.76 | CYP1A2 (0.56) | POLBLMNANPSR1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915806-B1 | QUINOLINE COMPOUND AND USE THEREOF | UNIV SHENYANG PHARMACEUTICAL (CN) | 2018-04-25 | — | — | EP | disclosed |
| US-9783499-B2 | Quinoline derivatives and their applications | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2017-10-10 | — | — | US | disclosed |
| US-20150307453-A1 | NOVEL QUINOLINE DERIVATIVES AND THEIR APPLICATIONS | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307453-A1 | NOVEL QUINOLINE DERIVATIVES AND THEIR APPLICATIONS | MET, RAF1, RET | POLB 4278/4885HTT 4338/4885LMNA 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.