Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | NQO1 | P15559 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | POR | P16435 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478498 | 0.72 | IDO1 (0.32) | IDO1LMNACYP2C9KDM4EMEN1 | |
| SCHEMBL14478500 | 0.72 | IDO1 (0.32) | IDO1LMNACYP2C9KDM4EMEN1 | |
| SCHEMBL92282 | 0.66 | — | — | |
| SCHEMBL894148 | 0.64 | — | — | |
| SCHEMBL494066 | 0.63 | — | — | |
| SCHEMBL6209797 | 0.61 | LMNA (0.38) | IDO1LMNACYP2C9KDM4EMEN1 | |
| SCHEMBL18268913 | 0.60 | LMNA (0.37) | IDO1LMNACYP2C9KDM4EMEN1 | |
| SCHEMBL14476781 | 0.60 | LMNA (0.37) | IDO1LMNACYP2C9KDM4EMEN1 | |
| SCHEMBL14476976 | 0.60 | LMNA (0.37) | IDO1LMNACYP2C9KDM4EMEN1 | |
| SCHEMBL17691092 | 0.60 | IDO1 (0.37) | IDO1LMNACYP2C9KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2742083-B1 | POLYARYLENE ETHER KETONES | SOLVAY SPECIALTY POLYMERS USA (US) | 2018-04-25 | — | — | EP | disclosed |