SCHEMBL2008237

SCHEMBL2008237

C[Si](C)(C)CCCCN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10788495 0.97 DNM1 (0.50)
SCHEMBL10699102 0.97 DNM1 (0.50)
SCHEMBL22584994 0.97 DNM1 (0.50)
SCHEMBL2003831 0.97 DNM1 (0.50)
SCHEMBL2005160 0.97 DNM1 (0.50)
SCHEMBL2007364 0.97 DNM1 (0.50)
SCHEMBL896776 0.90
SCHEMBL19713116 0.87
Hydrochloric Acid SCHEMBL16628517 0.87
Hydrochloric Acid SCHEMBL28578059 0.84 DNM1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112585228-A Polyimide varnish for coating conductor containing aromatic carboxylic acid and method for producing same PI尖端素材株式会社 2021-03-30 CN claimed
US-7964738-B2 Pharmaceutical compositions and methods of use of lipophilic, silicon-substituted, cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs and derivatives SILAMED, INC. (US) 2011-06-21 US claimed
US-20070129331-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES RND PHARMACEUTICALS, INC. (US) 2007-06-07 US claimed
EP-1737471-A2 PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES RND Pharmaceuticals (US) 2007-01-03 EP claimed
WO-2005102358-A2 SILICONE-SUBSTITUTED COX-2 SELECTIVE INHIBITORS RND PHARMACEUTICALS (US) 2005-11-03 WO claimed
CN-112585228-B Polyimide varnish for coating conductor containing aromatic carboxylic acid and method for producing same PI尖端素材株式会社 2022-07-08 CN disclosed
CN-108368606-B Method for the production of thin inorganic films 巴斯夫欧洲公司 2021-04-13 CN disclosed
CN-112585228-A Polyimide varnish for coating conductor containing aromatic carboxylic acid and method for producing same PI尖端素材株式会社 2021-03-30 CN disclosed
EP-3097103-B1 DIAZABICYCLO[4.3.1]DECANE DERIVATIVES FOR TREATMENT OF PSYCHIATRIC DISORDERS MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS (DE) 2017-11-15 EP disclosed
US-7964738-B2 Pharmaceutical compositions and methods of use of lipophilic, silicon-substituted, cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs and derivatives SILAMED, INC. (US) 2011-06-21 US disclosed
US-7909889-B2 Lightening and/or coloring human keratin fibers using at least one aminotrialkoxy silane or at least one aminotrialkenyloxy silane composition L'OREAL S.A. (FR) 2011-03-22 US disclosed
US-20100275387-A1 LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING AT LEAST ONE AMINOTRIALKOXY SILANE OR AT LEAST ONE AMINOTRIALKENYLOXY SILANE COMPOSITION L'OREAL S.A. (FR) 2010-11-04 US disclosed
EP-0553081-A1 PESTICIDES. ROUSSEL UCLAF (FR) 1993-08-04 EP disclosed
EP-0527007-A1 Process for preparation of primary aminoorganosilanes DOW CORNING CORPORATION (US) 1993-02-10 EP disclosed
US-5117024-A Hydrogenation with hydrogen gas of cyanoorganosilane in the presence of a supported cobalt catalyst DOW CORNING CORPORATION (US) 1992-05-26 US disclosed
WO-1991016301-A1 PESTICIDES THE WELLCOME FOUNDATION LIMITED (GB) 1991-10-31 WO disclosed
US-5002689-A Heat stable, soluble stabilizers LITHIUM CORPORATION OF AMERICA (US) 1991-03-26 US disclosed
US-4868189-A ANTICANCER AGENTS SANWA KAGAKU KENKYUSHO CO. (JP) 1989-09-19 US disclosed
EP-0280841-A2 Organo-silicone compounds and use thereof SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1988-09-07 EP disclosed
US-4412073-A Isocyanurate preparation by catalytic, aminosilyl initiated cyclotrimerization of isocyanates RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-10-25 US disclosed