SCHEMBL2008261

SCHEMBL2008261

CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](OC[C@H](COCc2ccccc2)NC(=O)OCC(Cl)(Cl)Cl)[C@@H](NC(=O)OCC(Cl)(Cl)Cl)[C@@H](O)[C@@H]1O

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 7/20 0.36
▸ CDC25B P30305 7/20 0.36
▸ PTPN2 P17706 5/20 0.36
▸ CDC25A P30304 3/20 0.36
▸ PTPN6 P29350 1/20 0.36
▸ PTPN11 Q06124 1/20 0.36
▸ PPARA Q07869 2/20 0.35
▸ KLK7 P49862 2/20 0.34
▸ KLK5 Q9Y337 2/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ GHSR Q92847 2/20 0.33
▸ PPARG P37231 1/20 0.32
▸ ANPEP P15144 2/20 0.32
▸ CTSS P25774 1/20 0.32
▸ TNF P01375 1/20 0.32
▸ ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2008260 1.00 PTPN1 (0.36) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL17227496 1.00 PTPN1 (0.36) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL14376675 0.91 PTPN1 (0.36) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL2002735 0.90 ANPEP (0.35) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL26263865 0.90 ANPEP (0.35) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL15501143 0.88 ANPEP (0.38) ANPEP
SCHEMBL2003090 0.88 ANPEP (0.38) ANPEP
SCHEMBL2003089 0.88 ANPEP (0.38) ANPEP
SCHEMBL14376674 0.87 BTN3A1 (0.35) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL25401991 0.83 ANPEP (0.31) ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1521762-B1 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORP (US) 2014-03-12 — — EP disclosed
US-7960523-B2 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor CORIXA CORPORATION (US) 2011-06-14 — — US disclosed
US-20080033155-A1 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORPORATION (US) 2008-02-07 — — US disclosed
US-7288640-B2 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor CORIXA CORPORATION (US) 2007-10-30 — — US disclosed
US-7232900-B2 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors and intermediates therefor CORIXA CORPORATION (US) 2007-06-19 — — US disclosed
WO-2006012425-A2 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORPORATION (US) 2006-02-02 — — WO disclosed
US-20050107600-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor CORIXA CORPORATION, A CORPORATION OF THE STATE OF DELAWARE (US) 2005-05-19 — — US disclosed
US-20040267007-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors and intermediates therefor CORIXA CORPORATION 2004-12-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040267007-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors and intermediates therefor DDOST, STT3A, STT3B PTPN1 2351/4885CDC25B 2644/4885PTPN2 2183/4885
US-20050107600-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor DDOST, AGL, GALE PTPN1 2254/4885CDC25B 2860/4885PTPN2 2127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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