Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18331409 | 0.90 | MAPT (0.37) | HPGDMAPTNPSR1RECQLLEF1 | |
| SCHEMBL20084819 | 0.89 | RXFP1 (0.35) | RXFP1MAPTLEF1F11KLKB1 | |
| SCHEMBL18332490 | 0.87 | RXFP1 (0.38) | RXFP1HPGDMAPTNPSR1F11 | |
| SCHEMBL10003424 | 0.84 | RXFP1 (0.47) | RXFP1HPGDMAPTNPSR1RECQL | |
| SCHEMBL10003427 | 0.84 | RXFP1 (0.47) | RXFP1HPGDMAPTNPSR1RECQL | |
| SCHEMBL21572135 | 0.83 | KMT2A (0.39) | RXFP1HPGDMAPTNPSR1F11 | |
| SCHEMBL18332517 | 0.83 | KMT2A (0.39) | RXFP1HPGDMAPTNPSR1F11 | |
| SCHEMBL11931249 | 0.80 | POLB (0.42) | RXFP1HPGDMAPTNPSR1RECQL | |
| SCHEMBL10002864 | 0.80 | POLB (0.42) | RXFP1HPGDMAPTNPSR1RECQL | |
| SCHEMBL18332352 | 0.80 | NPSR1 (0.40) | RXFP1HPGDMAPTNPSR1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312172-A1 | AMINOPYRAZOLE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-04-25 | — | — | EP | disclosed |