Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20084815 | 0.90 | RXFP1 (0.35) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL18332241 | 0.84 | ALDH1A1 (0.39) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL20084014 | 0.82 | ALDH1A1 (0.38) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL20085303 | 0.81 | ALDH1A1 (0.38) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL20084085 | 0.80 | HPGD (0.37) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL18331949 | 0.80 | ALDH1A1 (0.37) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL18331951 | 0.79 | ALDH1A1 (0.36) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL20084189 | 0.79 | ALDH1A1 (0.36) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL20084819 | 0.79 | RXFP1 (0.35) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL20084762 | 0.78 | HPGD (0.35) | MAPTALDH1A1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312172-B1 | AMINOPYRAZOLE DERIVATIVES USEFUL AS SRC KINASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2020-05-06 | — | — | EP | disclosed |
| EP-3312172-A1 | AMINOPYRAZOLE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-04-25 | — | — | EP | disclosed |
| WO-2016204261-A1 | AMINOPYRAZOLE DERIVATIVES | 中外製薬株式会社 | 2016-12-22 | — | — | WO | disclosed |