Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984470 | 0.95 | TSHR (0.61) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL3238852 | 0.93 | TSHR (0.58) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2829331 | 0.93 | TSHR (0.58) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8768045 | 0.87 | TSHR (0.56) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL25182060 | 0.87 | MEN1 (0.53) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL6314526 | 0.87 | MEN1 (0.53) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL1294405 | 0.87 | MEN1 (0.53) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL20247766 | 0.86 | TSHR (0.78) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2832820 | 0.86 | TSHR (0.56) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2829800 | 0.85 | TSHR (0.54) | TSHRMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180112121-A1 | POLYMERIC COMPOSITIONS AGGLOMERATING COMPOSITIONS, MODIFIED SOLID MATERIALS, AND METHODS FOR MAKING AND USING SAME | THE LUBRIZOL CORPORATION | 2018-04-26 | — | — | US | disclosed |