Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15844109 | 0.85 | CBFB (0.35) | NPBWR1TRPV1 | |
| SCHEMBL20088415 | 0.79 | HPGD (0.42) | NPBWR1TRPV1 | |
| SCHEMBL20088417 | 0.76 | NPBWR1 (0.39) | NPBWR1TRPV1 | |
| SCHEMBL20088414 | 0.74 | POLB (0.37) | — | |
| SCHEMBL20088411 | 0.74 | PDE3B (0.34) | NPBWR1TRPV1 | |
| SCHEMBL20088413 | 0.74 | NPBWR1 (0.45) | NPBWR1TRPV1 | |
| SCHEMBL17149423 | 0.70 | MAPT (0.37) | NPBWR1 | |
| SCHEMBL17449485 | 0.69 | KDM4E (0.37) | — | |
| SCHEMBL20094221 | 0.68 | CACNA1H (0.38) | — | |
| SCHEMBL15850783 | 0.68 | CACNA1H (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180111894-A1 | Benzimidazole Inhibitors of the Sodium Channel | DeGiacomo, Mark G. (US) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111894-A1 | Benzimidazole Inhibitors of the Sodium Channel | SCN1A, KCNJ11, KCNJ1 | NPBWR1 2176/4885TRPV1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.