SCHEMBL20089063

SCHEMBL20089063

c1ccc(N(c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-3)c2ccc3c(c2)C(c2ccccc2)(c2cccc4c2sc2ccccc24)c2ccccc2-3)cc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PARP14 Q460N5 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18118731 0.99 ALOX5 (0.36) ALOX5PARP14PDK2
SCHEMBL18118710 0.95 ALOX5 (0.38) ALOX5PDK2
SCHEMBL18118694 0.94 ALOX5 (0.39) ALOX5PARP14PDK2
SCHEMBL20089076 0.92 ALOX5 (0.33) ALOX5
SCHEMBL16995998 0.91 ALOX5 (0.44) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL16631093 0.91 ALOX5 (0.38) ALOX5PARP14
SCHEMBL16631107 0.91 ALOX5 (0.36) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL9916376 0.90 ALOX5 (0.43) ALOX5PARP14
SCHEMBL16996241 0.90 ALOX5 (0.43) ALOX5PARP14
SCHEMBL16882698 0.90 ALOX5 (0.34) ALOX5KDM4EMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10580993-B2 Amine compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-03-03 US disclosed
US-20180114906-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-04-26 US disclosed
US-20180114906-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-04-26 US disclosed