Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.37 |
| ▸ | RELA | Q04206 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19929461 | 0.89 | THRB (0.38) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20672698 | 0.83 | THRB (0.49) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20616102 | 0.83 | THRB (0.49) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18353288 | 0.83 | THRB (0.49) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12374423 | 0.83 | THRB (0.49) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20616070 | 0.82 | THRB (0.48) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20616090 | 0.82 | THRB (0.48) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22138769 | 0.82 | THRB (0.48) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20615639 | 0.82 | THRB (0.48) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20615638 | 0.82 | THRB (0.48) | NPC1LMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180112022-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC MATERIAL | DIC CORPORATION (JP) | 2018-04-26 | — | — | US | disclosed |
| US-20180112022-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC MATERIAL | DIC CORPORATION (JP) | 2018-04-26 | — | — | US | disclosed |