Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 2/20 | 0.37 |
| ▸ | S100A4 | P26447 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395626 | 0.89 | PDK2 (0.44) | PDK2KMT2ACYP1A2CYP2C19NR4A2 | |
| SCHEMBL22609096 | 0.89 | PDK2 (0.44) | PDK2KMT2ACYP1A2CYP2C19NR4A2 | |
| SCHEMBL11990868 | 0.83 | PDK2 (0.56) | PDK2KMT2ACYP1A2CYP2C19S100A4 | |
| SCHEMBL30322608 | 0.83 | PDK2 (0.56) | PDK2KMT2ACYP1A2CYP2C19S100A4 | |
| SCHEMBL12685311 | 0.81 | PDK2 (0.62) | PDK2KMT2AS100A4MEN1LMNA | |
| SCHEMBL32682807 | 0.81 | PDK2 (0.49) | PDK2KMT2ACYP1A2CYP2C19S100A4 | |
| SCHEMBL29419598 | 0.81 | PDK2 (0.49) | PDK2KMT2ACYP1A2CYP2C19S100A4 | |
| SCHEMBL5344736 | 0.81 | PDK2 (0.49) | PDK2KMT2ACYP1A2CYP2C19S100A4 | |
| SCHEMBL29800749 | 0.81 | PDK2 (0.62) | PDK2KMT2AS100A4MEN1LMNA | |
| SCHEMBL17816870 | 0.79 | PDK2 (0.61) | PDK2KMT2AS100A4MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180114922-A1 | COMPOUND AND PREPARATION METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE | BOE TECHNOLOGY GROUP CO. LTD. (CN) | 2018-04-26 | — | — | US | disclosed |
| US-20180114922-A1 | COMPOUND AND PREPARATION METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE | BOE TECHNOLOGY GROUP CO. LTD. (CN) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180114922-A1 | COMPOUND AND PREPARATION METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE | LEF1, TYR, LSS | PDK2 1838/4885KMT2A 2144/4885CYP1A2 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.