Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.50 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.50 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845993 | 1.00 | LCK (0.50) | LCKMAP2K3MAP2K6BTKMAP3K19 | |
| Hydrochloric Acid SCHEMBL10842830 | 0.98 | LCK (0.49) | LCKMAP2K3MAP2K6BTKMAP3K19 | |
| SCHEMBL30798875 | 0.83 | KDM4E (0.50) | HCRTR1HCRTR2KMT2AKDM4EGPR3 | |
| SCHEMBL335334 | 0.83 | KDM4E (0.50) | HCRTR1HCRTR2KMT2AKDM4EGPR3 | |
| SCHEMBL8237140 | 0.81 | HCRTR1 (0.45) | LCKMAP2K3MAP2K6BTKMAP3K19 | |
| SCHEMBL27671863 | 0.81 | KDM4E (0.49) | HCRTR1HCRTR2KMT2AKDM4EGPR3 | |
| SCHEMBL25500933 | 0.81 | HCRTR1 (0.42) | LCKMAP2K3MAP2K6BTKMAP3K19 | |
| SCHEMBL30310893 | 0.81 | GPR3 (0.41) | LCKMAP2K3MAP2K6BTKMAP3K19 | |
| SCHEMBL2008976 | 0.81 | HCRTR1 (0.45) | LCKMAP2K3MAP2K6BTKMAP3K19 | |
| Potassium Ion SCHEMBL10736971 | 0.80 | HCRTR1 (0.41) | LCKMAP2K3MAP2K6BTKMAP3K19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | claimed |
| CN-103764140-A | Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases | KOREA RES INST CHEM TECH | 2014-04-30 | — | — | CN | claimed |
| CN-118541353-A | Bis (hetero) aryl thioether (thio) amides as fungicidal compounds | 拜耳公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-116057056-A | Azabicyclo-substituted heterocyclic compounds as fungicides | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |
| CN-103764140-A | Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases | KOREA RES INST CHEM TECH | 2014-04-30 | — | — | CN | disclosed |
| US-7960394-B2 | 3,8-dimethyl-2-[4-(3-piperidin-1-ylpropoxy)phenyl]-4(3H)-quinazolinone; 6-chloro-3-methyl-2-[4-(3-piperidin-1-ylpropoxy)phenyl]pyrido[3,4-d]-pyrimidin-4(3H)-one; 2-[4-(1-cyclopentyl-4-piperidinyloxy)phenyl]-3-methylpyrido[2,3-d]-pyrimidin-4(3H)-one; treats metabolic, nervous system, vascular disorders | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2011-06-14 | — | — | US | disclosed |
| EP-1812007-A4 | PYRIDAZINE COMPOUNDS AND METHODS | UNIV NORTHWESTERN (US) | 2009-04-01 | — | — | EP | disclosed |
| US-20080275069-A1 | Quinazoline Derivative | MSD K.K. (JP) | 2008-11-06 | — | — | US | disclosed |
| WO-2008035209-A2 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | METHYLGENE INC. (CA) | 2008-03-27 | — | — | WO | disclosed |
| EP-1812007-A2 | PYRIDAZINE COMPOUNDS AND METHODS | Northwestern University (US) | 2007-08-01 | — | — | EP | disclosed |
| EP-1757594-A1 | QUINAZOLINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |
| US-20060211636-A1 | Macrolide Antibiotics | ALIHODZIC SULEJMAN | 2006-09-21 | — | — | US | disclosed |
| WO-2006050359-A2 | PYRIDAZINE COMPOUNDS AND METHODS | NORTHWESTERN UNIVERSITY (US) | 2006-05-11 | — | — | WO | disclosed |
| US-20050215495-A1 | Macrolide antibiotics | ALIHODZIC SULEJMAN | 2005-09-29 | — | — | US | disclosed |
| EP-1363925-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002050091-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |
| US-4699651-A | Use of certain cinnoline-4-carboxylic acids and congeners thereof for controlling the growth of unwanted plants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-13 | — | — | US | disclosed |
| EP-0212726-A2 | Herbicidal cinnoline compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215495-A1 | Macrolide antibiotics | IL1R1, MRPL12, RPS21 | LCK 2913/4885MAP2K3 4153/4885MAP2K6 4317/4885 |
| US-20080275069-A1 | Quinazoline Derivative | HRH3, HRH4, HRH2 | LCK 584/4885MAP2K3 399/4885MAP2K6 419/4885 |
| US-20060211636-A1 | Macrolide Antibiotics | IL1R1, MRPL12, RPS21 | LCK 2913/4885MAP2K3 4153/4885MAP2K6 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.