SCHEMBL20090780 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	IDO1	P14902	6/20	0.44

▸	ALDH1A1	P00352	5/20	0.40

▸	AURKB	Q96GD4	1/20	0.39

▸	IKBKB	O14920	1/20	0.39

▸	MAPT	P10636	6/20	0.38

▸	GAA	P10253	4/20	0.38

▸	NPY1R	P25929	1/20	0.38

▸	LMNA	P02545	4/20	0.38

▸	TDP1	Q9NUW8	2/20	0.38

▸	TP53	P04637	1/20	0.37

▸	SMN1; SMN2	Q16637	1/20	0.37

▸	MEN1	O00255	1/20	0.37

▸	MAPK1	P28482	1/20	0.37

▸	KMT2A	Q03164	1/20	0.37

▸	NPSR1	Q6W5P4	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17624208	0.88	IDO1 (0.52)	IDO1ALDH1A1MAPTLMNATP53
SCHEMBL20198880	0.88	IDO1 (0.47)	IDO1ALDH1A1AURKBMAPTLMNA
SCHEMBL20090579	0.87	IDO1 (0.42)	IDO1
SCHEMBL147068	0.86	IDO1 (0.49)	IDO1ALDH1A1MAPTGAALMNA
SCHEMBL30449652	0.86	IDO1 (0.49)	IDO1ALDH1A1MAPTGAALMNA
SCHEMBL30448914	0.86	IDO1 (0.49)	IDO1ALDH1A1MAPTGAALMNA
SCHEMBL147069	0.86	IDO1 (0.49)	IDO1ALDH1A1MAPTGAALMNA
SCHEMBL20198881	0.85	IDO1 (0.46)	IDO1ALDH1A1AURKBMAPTGAA
SCHEMBL20090592	0.85	IDO1 (0.43)	IDO1MEN1KMT2A
SCHEMBL20090582	0.85	IDO1 (0.45)	IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018072697-A1	OXADIAZOLE RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND INTERMEDIATE, COMPOSITE, AND APPLICATION THEREOF	上海医药集团股份有限公司	2018-04-26	—	—	WO	disclosed