Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA7 | P43166 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20090792 | 0.88 | CA12 (0.61) | CA12CA1CA7CA9CA14 | |
| SCHEMBL20090815 | 0.86 | KDM4E (0.54) | CA12CA1CA7CA9CA14 | |
| SCHEMBL2608260 | 0.85 | TSHR (0.53) | CA12CA1CA7CA9CA14 | |
| SCHEMBL4580984 | 0.82 | CA12 (0.72) | CA12CA1CA7CA9CA14 | |
| SCHEMBL20090793 | 0.82 | TSHR (0.61) | CA12CA1CA7CA9CA14 | |
| SCHEMBL6395001 | 0.82 | CA12 (0.72) | CA12CA1CA7CA9CA14 | |
| SCHEMBL20090820 | 0.82 | NPC1 (0.53) | CA12CA1CA7CA9CA14 | |
| SCHEMBL10061434 | 0.81 | KDM4E (0.48) | CA12CA1CA7CA9CA14 | |
| SCHEMBL8148439 | 0.81 | LMNA (0.68) | CA12CA1CA7CA9CA14 | |
| SCHEMBL8149982 | 0.81 | CA12 (0.54) | CA12CA1CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3529333-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| EP-3529332-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| US-20190264105-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-08-29 | — | — | US | disclosed |
| WO-2019154740-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-08-15 | — | — | WO | disclosed |
| US-20190241808-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-08-08 | — | — | US | disclosed |
| WO-2018073158-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2018-04-26 | — | — | WO | disclosed |
| WO-2018073159-A2 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2018-04-26 | — | — | WO | disclosed |