SCHEMBL20090832

SCHEMBL20090832

C=C(C)C(=O)OC1CCC(OC(=O)C(=C)CC)CC1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
ALDH1A1 P00352 2/20 0.37
TSHR P16473 3/20 0.34
EPHX1 P07099 1/20 0.33
NAAA Q02083 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3268433 0.92 EPHX1 (0.37) THRBALDH1A1TSHREPHX1NAAA
SCHEMBL21761419 0.87 EPHX1 (0.34) EPHX1NAAA
SCHEMBL342182 0.86 ALDH1A1 (0.46) THRBALDH1A1TSHREPHX1NAAA
SCHEMBL25278 0.86
SCHEMBL372980 0.86 ALDH1A1 (0.46) THRBALDH1A1TSHREPHX1NAAA
SCHEMBL27508235 0.85 CYP19A1 (0.40) ALDH1A1EPHX1NAAA
SCHEMBL7022735 0.85 EPHX1 (0.43) ALDH1A1EPHX1NAAA
SCHEMBL27529211 0.85 EPHX1 (0.47) ALDH1A1TSHREPHX1NAAA
SCHEMBL29117656 0.83 EPHX1 (0.50) ALDH1A1TSHREPHX1NAAA
SCHEMBL29117755 0.83 EPHX1 (0.50) ALDH1A1TSHREPHX1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019233913-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2019-12-12 WO disclosed
WO-2019154740-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2019-08-15 WO disclosed
WO-2018073159-A2 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2018-04-26 WO disclosed