Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20082335 | 1.00 | TSHR (0.41) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL20082320 | 1.00 | TSHR (0.41) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL8626031 | 1.00 | TSHR (0.41) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL21371146 | 1.00 | TSHR (0.41) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL20091169 | 1.00 | TSHR (0.41) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL2749084 | 0.90 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL30828899 | 0.90 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL13422928 | 0.90 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL805599 | 0.90 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL24066052 | 0.83 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018074926-A1 | BIS-DIOX(OL)ANE COMPOUNDS | KONINKLIJKE COOPERATIE COSUN U.A. (NL) | 2018-04-26 | — | — | WO | disclosed |