Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | PGD | P52209 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805599 | 1.00 | TSHR (0.44) | TSHRLMNAALDH1A1PPM1BPTPN1 | |
| SCHEMBL2749084 | 1.00 | TSHR (0.44) | TSHRLMNAALDH1A1PPM1BPTPN1 | |
| SCHEMBL13422928 | 1.00 | TSHR (0.44) | TSHRLMNAALDH1A1PPM1BPTPN1 | |
| SCHEMBL12540224 | 0.92 | LMNA (0.41) | TSHRLMNAALDH1A1PPM1BPTPN1 | |
| SCHEMBL21001793 | 0.92 | TSHR (0.44) | TSHRLMNAALDH1A1PPM1BPTPN1 | |
| SCHEMBL24066052 | 0.92 | TSHR (0.44) | TSHRLMNAALDH1A1PPM1BPTPN1 | |
| SCHEMBL29183553 | 0.92 | TSHR (0.44) | TSHRLMNAALDH1A1PPM1BPTPN1 | |
| SCHEMBL803723 | 0.92 | LMNA (0.41) | TSHRLMNAALDH1A1PPM1BPTPN1 | |
| SCHEMBL6530767 | 0.92 | TSHR (0.44) | TSHRLMNAALDH1A1PPM1BPTPN1 | |
| SCHEMBL28544198 | 0.92 | TSHR (0.44) | TSHRLMNAALDH1A1PPM1BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704120-B1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | JUBILANT EPISCRIBE LLC (US) | 2024-03-06 | — | — | EP | disclosed |