SCHEMBL200919

SCHEMBL200919

C1=CC2CC1CC2c1ccc(-c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 13/20 0.55
MAOB P27338 9/20 0.55
MAOA P21397 7/20 0.38
CYP2C19 P33261 4/20 0.38
CYP2B6 P20813 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C9 P11712 2/20 0.38
LMNA P02545 2/20 0.38
TAAR1 Q96RJ0 2/20 0.38
HDAC6 Q9UBN7 1/20 0.38
CYP3A4 P08684 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CYP2A6 P11509 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2C P28335 1/20 0.38
ADRA1A P35348 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21525759 0.92 KDM1A (0.42) KDM1AMAOBLMNAHDAC6SLC6A2
SCHEMBL21525760 0.92 KDM1A (0.42) KDM1AMAOBLMNAHDAC6SLC6A2
SCHEMBL10160393 0.90 KDM1A (0.46) KDM1AMAOBCYP2D6LMNACYP3A4
SCHEMBL109753 0.90 MAOB (0.46) KDM1AMAOBMAOACYP2C19CYP2B6
SCHEMBL10160447 0.89 KDM1A (0.45) KDM1AMAOBCYP2C19CYP1A2CYP2D6
SCHEMBL16530012 0.88 KDM1A (0.38) KDM1AMAOBMAOALMNASLC6A2
SCHEMBL6234699 0.88 KDM1A (0.38) KDM1AMAOBMAOALMNASLC6A2
SCHEMBL31173794 0.85 KDM1A (0.41) KDM1AMAOBHDAC6SLC6A2HTR2C
SCHEMBL31173793 0.85 KDM1A (0.41) KDM1AMAOBHDAC6SLC6A2HTR2C
SCHEMBL22471993 0.83 MAOB (0.41) KDM1AMAOBMAOACYP2C19CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7101496-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-09-05 US claimed
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
EP-1623967-B1 NORBORNENE DERIVATIVE, NORBORNENE POLYMER PRODUCED BY RING-OPENING (CO)POLYMERIZATION, AND PROCESS FOR PRODUCING THE POLYMER BY RING-OPENING (CO)POLYMERIZATION JSR CORP (JP) 2012-01-18 EP disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
EP-2322960-A1 Optical film, polarizer and liquid crystal display JSR Corporation (JP) 2011-05-18 EP disclosed
US-7759437-B2 Norbornene derivative, norbornene polymer produced by ring-opening (co)polymerization, and process for producing the polymer by ring-opening (co)polymerization JSR CORPORATION (JP) 2010-07-20 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-7675587-B2 Polarizing plate and process for producing the same JSR CORPORATION (JP) 2010-03-09 US disclosed
US-7646457-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
EP-1623967-A1 NORBORNENE DERIVATIVE, NORBORNENE POLYMER PRODUCED BY RING-OPENING (CO)POLYMERIZATION, AND PROCESS FOR PRODUCING THE POLYMER BY RING-OPENING (CO)POLYMERIZATION JSR Corporation (JP) 2006-02-08 EP disclosed
US-6846890-B2 Norbornene derivative and norbornene polymer obtained therefrom through ring opening polymerization JSR CORPORATION (JP) 2005-01-25 US disclosed
US-20040242824-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING OPENING POLYMERIZATION JSR CORPORATION (JP) 2004-12-02 US disclosed
US-20040242823-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-12-02 US disclosed
EP-1459107-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-09-22 EP disclosed
EP-1435350-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING-OPENING POLYMERIZATION JSR Corporation (JP) 2004-07-07 EP disclosed
EP-1397709-A1 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-17 EP disclosed
US-20040047056-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-11 US disclosed
WO-2003056365-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2003-07-10 WO disclosed
WO-2002088783-A1 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed