SCHEMBL109753

SCHEMBL109753

C1=CC2CC1CC2c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 11/20 0.46
KDM1A O60341 8/20 0.46
MAOA P21397 7/20 0.46
HTR2C P28335 7/20 0.46
CYP2C19 P33261 4/20 0.46
CYP2B6 P20813 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C9 P11712 2/20 0.46
LMNA P02545 2/20 0.46
TAAR1 Q96RJ0 2/20 0.46
CYP3A4 P08684 1/20 0.46
HTR1A P08908 1/20 0.46
ADRA2A P08913 1/20 0.46
CYP2A6 P11509 1/20 0.46
SLC6A2 P23975 1/20 0.46
ADRA1A P35348 1/20 0.46
DRD3 P35462 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KCNH2 Q12809 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22471993 0.92 MAOB (0.41) MAOBKDM1AMAOAHTR2CCYP2C19
SCHEMBL200919 0.90 KDM1A (0.55) MAOBKDM1AMAOAHTR2CCYP2C19
SCHEMBL16530012 0.89 KDM1A (0.38) MAOBKDM1AMAOAHTR2CLMNA
SCHEMBL6234699 0.89 KDM1A (0.38) MAOBKDM1AMAOAHTR2CLMNA
SCHEMBL5720302 0.85 GAA (0.36) MAOBKDM1AMAOAHTR2CCYP2C19
SCHEMBL21525760 0.84 KDM1A (0.42) MAOBKDM1AHTR2CLMNASLC6A2
SCHEMBL21525759 0.84 KDM1A (0.42) MAOBKDM1AHTR2CLMNASLC6A2
SCHEMBL16704816 0.84 CYP3A4 (0.40) MAOBKDM1AMAOAHTR2CCYP2C19
SCHEMBL12090467 0.84 CYP3A4 (0.40) MAOBKDM1AMAOAHTR2CCYP2C19
SCHEMBL16715909 0.84 CYP3A4 (0.40) MAOBKDM1AMAOAHTR2CCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3112 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138757-A1 ROCKET MOTOR CESARONI AEROSPACE INCORPORATED (US) 2026-05-21 US claimed
US-12545438-B2 Rocket motor CESARONI AEROSPACE INCORPORATED (US) 2026-02-10 US claimed
US-20250388744-A1 HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC AND ANHYDRIDE FUNCTIONALITY AND MELAMINE PROMERUS, LLC (US) 2025-12-25 US claimed
EP-4584309-A1 POLYCYCLIC-OLEFINIC POLYMERS CONTAINING ACRYLATE FUNCTIONALITY WITH ACRYLATE/MALEIMIDE CROSSLINKERS AS B-STAGEABLE COMPOSITIONS FOR LOW LOSS APPLICATIONS Promerus, LLC (US) 2025-07-16 EP claimed
US-20250177927-A1 SUPPORTED MEMBRANES BY THERMAL AND UV INITITATED MASS POLYMERIZATION PROMERUS, LLC (US) 2025-06-05 US claimed
EP-2970522-B1 IN-MOLD COATING OF ROMP POLYMERS MATERIA INC (US) 2025-05-21 EP claimed
US-12303461-B1 Pharmaceutical container with pH protective layer deposited by atomic layer deposition INNOVATIVE SCIENTIFIC PRODUCTS, INC. (US) 2025-05-20 US claimed
CN-119998382-A Flame retardant compositions comprising polycycloolefinic polymers containing olefinic functionality for forming low loss films with improved dielectric and thermal properties 普罗米鲁斯有限责任公司 2025-05-13 CN claimed
CN-119968406-A Polycyclic olefin polymers containing acrylate functionality and acrylate/maleimide crosslinkers as B-stageable compositions in low loss applications 普罗米鲁斯有限责任公司 2025-05-09 CN claimed
CN-119948116-A Coating composition with polyolefin network structure SWIMC有限公司 2025-05-06 CN claimed
EP-0446051-A1 Process for the production of cycloolefin-based random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-09-11 EP claimed
EP-0430026-A2 Copolymer for use in preparing prepregs, printed circuit wiring boards prepared from such prepregs and processes for preparing such printed circuit wiring boards THE B.F. GOODRICH COMPANY (US) 1991-06-05 EP claimed
CN-1051921-A Copolymer for preparing impregnated green sheet, printed wiring board made from the green sheet, and method for producing wiring board GOODRICH CO B F (US) 1991-06-05 CN claimed
EP-0426142-A2 Method of making ring-opened polynorbornene polymers using pot life extending agents NIPPON ZEON CO., LTD. (JP) 1991-05-08 EP claimed
US-4900799-A Metathesis polymerization of cycloolefins TEIJIN LIMITED (JP) 1990-02-13 US claimed
EP-0251033-A2 Metathesis polymerization of cycloolefins HERCULES INCORPORATED (US) 1988-01-07 EP claimed
US-4442011-A ETHYLENE-PROPYLENE-PHENYLNORBORNENE TERPOLYMER EXXON RESEARCH AND ENGINEERING CO. (US) 1984-04-10 US claimed
US-4250063-A COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-02-10 US claimed
US-4176220-A COORDINATION CATALYST JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1979-11-27 US claimed
US-4068063-A Catalyst composition for ring-opening polymerization of norbornene derivatives and process for polymerizing same JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1978-01-10 US claimed