Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.60 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009287 | 1.00 | KCNH2 (0.60) | KCNH2TNNC1L3MBTL1CNR1SMN1; SMN2 | |
| SCHEMBL27610241 | 0.92 | KCNH2 (0.58) | KCNH2TNNC1L3MBTL1SMN1; SMN2AHR | |
| SCHEMBL6046924 | 0.88 | TNNC1 (0.55) | KCNH2TNNC1FAAHTRPV1 | |
| SCHEMBL27629497 | 0.84 | KCNH2 (0.53) | KCNH2AHR | |
| SCHEMBL13824133 | 0.84 | KCNH2 (0.53) | KCNH2AHR | |
| SCHEMBL24060796 | 0.84 | KCNH2 (0.54) | KCNH2TNNC1L3MBTL1CNR1TRPV1 | |
| SCHEMBL9187767 | 0.82 | TNNC1 (0.49) | KCNH2TNNC1SMN1; SMN2FAAHTRPV1 | |
| SCHEMBL9421147 | 0.82 | TNNC1 (0.49) | KCNH2TNNC1SMN1; SMN2FAAHTRPV1 | |
| SCHEMBL1277033 | 0.81 | TNNC1 (0.55) | TNNC1CNR1TRPV1 | |
| SCHEMBL1140656 | 0.81 | TNNC1 (0.51) | KCNH2TNNC1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960571-B2 | Silicon-based cross-coupling reagent and production method of organic compound using the same | KYOTO UNIVERSITY (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | KYOTO UNIVERSITY (JP) | 2009-03-12 | — | — | US | disclosed |
| EP-0314003-B1 | PROCESS FOR THE PREPARATION OF 1-ARYL ALKENES-1 | BASF Aktiengesellschaft (DE) | 1991-08-21 | — | — | EP | disclosed |
| US-4929786-A | DEHYDRATION, ARYLPHOSPHITE CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1990-05-29 | — | — | US | disclosed |
| EP-0314003-A2 | Process for the preparation of 1-aryl alkenes-1 | BASF Aktiengesellschaft (DE) | 1989-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | DNMT1, TET3, CTCF | KCNH2 618/4885TNNC1 3618/4885L3MBTL1 3155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.