Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20093004 | 0.92 | TYK2 (0.48) | TYK2 | |
| SCHEMBL20092428 | 0.90 | TYK2 (0.49) | TYK2 | |
| SCHEMBL20092363 | 0.82 | TYK2 (0.48) | TYK2 | |
| SCHEMBL20092488 | 0.80 | TYK2 (0.53) | TYK2 | |
| SCHEMBL20092337 | 0.80 | TYK2 (0.46) | TYK2 | |
| SCHEMBL20093157 | 0.77 | TYK2 (0.67) | TYK2 | |
| SCHEMBL20092987 | 0.77 | TYK2 (0.67) | TYK2 | |
| SCHEMBL20092216 | 0.76 | TYK2 (0.68) | TYK2 | |
| SCHEMBL20092418 | 0.76 | TYK2 (0.68) | TYK2 | |
| SCHEMBL20092083 | 0.73 | TYK2 (0.51) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075937-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2018-04-26 | — | — | WO | disclosed |