Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.73 |
| ▸ | PPARD | Q03181 | 1/20 | 0.64 |
| ▸ | LIFR | P42702 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4840400 | 0.88 | NR1H4 (0.69) | NR1H4LIFR | |
| SCHEMBL4835608 | 0.88 | NR1H4 (0.69) | NR1H4PPARDLIFR | |
| SCHEMBL2083796 | 0.88 | NR1H4 (0.69) | NR1H4LIFR | |
| SCHEMBL4835579 | 0.88 | NR1H4 (0.71) | NR1H4PPARDLIFR | |
| SCHEMBL4797323 | 0.87 | NR1H4 (0.78) | NR1H4LIFR | |
| SCHEMBL19499079 | 0.87 | NR1H4 (0.82) | NR1H4PPARDLIFR | |
| SCHEMBL4840276 | 0.87 | NR1H4 (0.70) | NR1H4PPARDLIFR | |
| SCHEMBL4837149 | 0.86 | NR1H4 (0.66) | NR1H4LIFR | |
| SCHEMBL4838421 | 0.86 | NR1H4 (0.76) | NR1H4PPARDLIFR | |
| SCHEMBL3994761 | 0.85 | NR1H4 (0.69) | NR1H4PPARDLIFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3529247-B1 | HETEROCYCLIC FXR MODULATORS | HEPAGENE THERAPEUTICS HK LTD (HK) | 2021-08-18 | — | — | EP | disclosed |
| WO-2018075207-A1 | HETEROCYCLIC FXR MODULATORS | HEPAGENE THERAPEUTICS, INC. (VG) | 2018-04-26 | — | — | WO | disclosed |