Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.70 |
| ▸ | PPARD | Q03181 | 3/20 | 0.70 |
| ▸ | LIFR | P42702 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838421 | 0.90 | NR1H4 (0.76) | NR1H4PPARDLIFR | |
| SCHEMBL20094448 | 0.87 | NR1H4 (0.73) | NR1H4PPARDLIFR | |
| SCHEMBL4835579 | 0.86 | NR1H4 (0.71) | NR1H4PPARDLIFR | |
| SCHEMBL4838231 | 0.84 | NR1H4 (0.85) | NR1H4PPARDLIFR | |
| SCHEMBL4598944 | 0.83 | NR1H4 (0.87) | NR1H4PPARDLIFR | |
| SCHEMBL4797323 | 0.83 | NR1H4 (0.78) | NR1H4LIFR | |
| SCHEMBL3994761 | 0.83 | NR1H4 (0.69) | NR1H4PPARDLIFR | |
| SCHEMBL19499079 | 0.83 | NR1H4 (0.82) | NR1H4PPARDLIFR | |
| SCHEMBL4435961 | 0.83 | NR1H4 (0.86) | NR1H4PPARDLIFR | |
| SCHEMBL24425708 | 0.83 | NR1H4 (1.00) | NR1H4PPARDLIFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319109-B2 | Farnesoid X receptor agonists | SMITH KLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |
| US-20060258725-A1 | Farnesoid x receptor agonists | SMITHKLINE BEECHAM CORPORATION | 2006-11-16 | — | — | US | disclosed |
| EP-1562915-A1 | FARNESOID X RECEPTOR AGONISTS | SmithKline Beecham Corporation (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004048349-A1 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258725-A1 | Farnesoid x receptor agonists | NR1H4, GPBAR1, NR1H2 | NR1H4 1/4885PPARD 178/4885LIFR 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.