Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.30 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.30 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.30 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094529 | 0.78 | CRBN (0.32) | — | |
| SCHEMBL5176269 | 0.75 | ALDH1A1 (0.47) | ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7743899 | 0.75 | CRBN (0.33) | CACNA1CSCN5APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL5176262 | 0.74 | POLB (0.35) | ALDH1A1 | |
| SCHEMBL5176267 | 0.74 | POLB (0.35) | ALDH1A1 | |
| SCHEMBL20094695 | 0.73 | TSHR (0.38) | ALDH1A1 | |
| SCHEMBL5176358 | 0.72 | CYP2C9 (0.33) | ALDH1A1 | |
| SCHEMBL909866 | 0.72 | — | — | |
| SCHEMBL15502243 | 0.72 | — | — | |
| SCHEMBL14553254 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075842-A1 | CONDENSED BENZODIAZEPINE DERIVATIVES AND CONJUGATES MADE THEREFROM | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-04-26 | — | — | WO | disclosed |