Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22788593 | 1.00 | NCEH1 (0.31) | NCEH1KDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL18123700 | 0.93 | NCEH1 (0.34) | NCEH1KDM4ECA1CA2MAPT | |
| SCHEMBL29879818 | 0.93 | NCEH1 (0.34) | NCEH1KDM4ECA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL20816193 | 0.92 | NCEH1 (0.34) | NCEH1KDM4ECA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL22772349 | 0.92 | NCEH1 (0.34) | NCEH1KDM4ECA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL20816206 | 0.91 | NCEH1 (0.33) | NCEH1KDM4ECA1CA2MAPT | |
| SCHEMBL20816205 | 0.90 | CA1 (0.36) | NCEH1KDM4ECA1CA2MAPT | |
| Sulfuric Acid SCHEMBL29880179 | 0.89 | CA1 (0.35) | NCEH1KDM4ECA1CA2MAPT | |
| Water SCHEMBL29880008 | 0.89 | CA1 (0.35) | NCEH1KDM4ECA1CA2MAPT | |
| SCHEMBL22536801 | 0.88 | CA1 (0.36) | NCEH1KDM4ECA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10183925-B2 | Substituted naphtho[2,3-b]furans as water-soluble prodrugs for preventing and/or treating cancer | BOSTON BIOMEDICAL, INC. (US) | 2019-01-22 | — | — | US | disclosed |
| US-20180111914-A1 | WATER-SOLUBLE PRODRUGS | BOSTON BIOMEDICAL, INC. (US) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111914-A1 | WATER-SOLUBLE PRODRUGS | NR0B2, NR0B1, AVPR1B | NCEH1 1245/4885KDM4E 3369/4885ADRB2 146/4885 |
| US-10183925-B2 | Substituted naphtho[2,3-b]furans as water-soluble prodrugs for preventing and/or treating cancer | NR0B1, NR0B2, NR2C2 | NCEH1 966/4885KDM4E 3479/4885ADRB2 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.