Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095683 | 1.00 | TDP1 (0.31) | TDP1 | |
| SCHEMBL20096001 | 0.92 | TDP1 (0.32) | TDP1 | |
| SCHEMBL9359755 | 0.84 | ALDH1A1 (0.40) | — | |
| SCHEMBL21316451 | 0.84 | ALDH1A1 (0.33) | — | |
| SCHEMBL12133506 | 0.78 | TDP1 (0.38) | TDP1 | |
| SCHEMBL14755102 | 0.75 | NR1H2 (0.31) | — | |
| SCHEMBL25589748 | 0.75 | — | — | |
| SCHEMBL19968074 | 0.74 | HTR2A (0.35) | TDP1 | |
| SCHEMBL661220 | 0.71 | TDP1 (0.42) | TDP1 | |
| SCHEMBL613375 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |