Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20063676 | 0.84 | SCN9A (0.44) | SCN9A | |
| SCHEMBL20072812 | 0.83 | SCN9A (0.49) | SCN9AKDM4E | |
| SCHEMBL20063697 | 0.82 | SCN9A (0.46) | SCN9A | |
| SCHEMBL19634090 | 0.82 | HTR2A (0.38) | KDM4ETSHR | |
| SCHEMBL20095534 | 0.81 | HTR2A (0.36) | KDM4ETSHR | |
| SCHEMBL20256130 | 0.80 | CYP1A2 (0.37) | SCN9AKDM4ETSHR | |
| SCHEMBL20256699 | 0.80 | KDM4E (0.38) | KDM4ETSHR | |
| SCHEMBL20256424 | 0.80 | SCN1A (0.36) | KDM4ETSHR | |
| SCHEMBL20256524 | 0.80 | KDM4E (0.36) | KDM4ETSHR | |
| SCHEMBL20256513 | 0.79 | SCN1A (0.44) | KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |