Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 12/20 | 0.59 |
| ▸ | SCN8A | Q9UQD0 | 12/20 | 0.59 |
| ▸ | SCN5A | Q14524 | 10/20 | 0.59 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16757015 | 0.88 | SCN1A (0.62) | SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL31735520 | 0.85 | SCN1A (0.59) | SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL16757123 | 0.82 | SCN5A (0.55) | SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL31735325 | 0.78 | SCN9A (0.53) | SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL20653711 | 0.77 | SCN1A (0.57) | SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL20256486 | 0.77 | SCN5A (0.79) | SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL20259132 | 0.77 | SCN5A (0.79) | SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL14921432 | 0.77 | SCN5A (0.53) | SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL29835250 | 0.77 | SCN5A (0.53) | SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL20095679 | 0.76 | SCN5A (0.58) | SCN1ASCN8ASCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |