Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 6/20 | 0.58 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.58 |
| ▸ | SCN1A | P35498 | 5/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 15/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | SCN2B | O60939 | 2/20 | 0.49 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095172 | 0.88 | SCN5A (0.61) | SCN5ASCN8ASCN1ASCN9ACYP3A4 | |
| SCHEMBL20095711 | 0.88 | SCN9A (0.50) | SCN5ASCN8ASCN1ASCN9ACYP3A4 | |
| Hydrochloric Acid SCHEMBL20486310 | 0.87 | SCN5A (0.60) | SCN5ASCN8ASCN1ASCN9ACYP3A4 | |
| SCHEMBL20095723 | 0.85 | SCN9A (0.48) | SCN5ASCN8ASCN1ASCN9ACYP3A4 | |
| SCHEMBL20095732 | 0.81 | SCN1A (0.50) | SCN5ASCN8ASCN1ASCN9A | |
| SCHEMBL17454965 | 0.78 | SCN1A (0.50) | SCN5ASCN8ASCN1ASCN9ACYP3A4 | |
| SCHEMBL29835236 | 0.78 | SCN1A (0.59) | SCN5ASCN8ASCN1ASCN9ACYP3A4 | |
| SCHEMBL23140833 | 0.77 | SCN1A (0.49) | SCN5ASCN8ASCN1ASCN9ACYP3A4 | |
| SCHEMBL20259316 | 0.76 | SCN1A (0.64) | SCN5ASCN8ASCN1ASCN9ASCN1B | |
| SCHEMBL20095908 | 0.76 | SCN1A (0.59) | SCN5ASCN8ASCN1ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019165290-A1 | PYRIDINE-SULFONAMIDE COMPOUNDS AND THEIR USE AGAINST PAIN AND RELATED CONDITIONS | GENENTECH, INC. (US) | 2019-08-29 | — | — | WO | disclosed |
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |