Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 7/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.33 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457010 | 1.00 | KAT2B (0.35) | KAT2BLATS1IKZF2IKZF1 | |
| SCHEMBL13881962 | 0.98 | KAT2B (0.36) | KAT2BLATS1IKZF2IKZF1 | |
| SCHEMBL16684253 | 0.98 | KAT2B (0.36) | KAT2BLATS1IKZF2IKZF1 | |
| SCHEMBL3975067 | 0.98 | KAT2B (0.36) | KAT2BLATS1IKZF2IKZF1 | |
| SCHEMBL10742576 | 0.98 | KAT2B (0.36) | KAT2BLATS1IKZF2IKZF1 | |
| SCHEMBL10742569 | 0.98 | KAT2B (0.36) | KAT2BLATS1IKZF2IKZF1 | |
| SCHEMBL11456240 | 0.98 | KAT2B (0.36) | KAT2BLATS1IKZF2IKZF1 | |
| SCHEMBL11456241 | 0.98 | KAT2B (0.36) | KAT2BLATS1IKZF2IKZF1 | |
| SCHEMBL11461873 | 0.93 | KAT2B (0.36) | KAT2BLATS1 | |
| SCHEMBL11461874 | 0.93 | KAT2B (0.36) | KAT2BLATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |