Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096202 | 1.00 | SLC6A4 (0.49) | SLC6A4HTR1AHTR7KDM1AKDM1B | |
| SCHEMBL434606 | 0.84 | KDM1A (0.52) | SLC6A4HTR1AKDM1AKDM1BHTR2C | |
| SCHEMBL11920714 | 0.79 | KDM1A (0.44) | SLC6A4HTR1AKDM1AKDM1BHTR2C | |
| SCHEMBL10091165 | 0.79 | KDM1A (0.44) | SLC6A4HTR1AKDM1AKDM1BHTR2C | |
| Acetaldehyde SCHEMBL27752382 | 0.77 | KDM1A (0.42) | SLC6A4HTR1AKDM1AKDM1BHTR2C | |
| Acetone SCHEMBL27752381 | 0.77 | DRD4 (0.45) | KDM1AKDM1BKDM4EGAA | |
| SCHEMBL434672 | 0.76 | KDM4E (0.50) | SLC6A4HTR1AKDM1AKDM1BHTR2C | |
| SCHEMBL316350 | 0.76 | KDM4E (0.55) | SLC6A4HTR1AKDM1AKDM1BHTR2C | |
| SCHEMBL22321329 | 0.75 | KDM4E (0.46) | SLC6A4HTR1AKDM1AKDM1BHTR2C | |
| SCHEMBL22321328 | 0.75 | KDM4E (0.46) | SLC6A4HTR1AKDM1AKDM1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |