Sugi Predict

Sugi Predict / Compounds / SCHEMBL434606

SCHEMBL434606

SCHEMBL434606

Fc1ccccc1C1CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 5/20 0.52
▸ KDM1B Q8NB78 1/20 0.52
▸ KDM4E B2RXH2 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ ADRA1D P25100 1/20 0.44
▸ ADRA1A P35348 1/20 0.44
▸ ADRA1B P35368 1/20 0.44
▸ HTR2C P28335 2/20 0.44
▸ HTR2B P41595 1/20 0.44
▸ HTR1A P08908 4/20 0.43
▸ SLC6A2 P23975 4/20 0.43
▸ SLC6A4 P31645 4/20 0.43
▸ SLC6A3 Q01959 3/20 0.43
▸ GRM2 Q14416 2/20 0.42
▸ DRD2 P14416 1/20 0.42
▸ DRD3 P35462 1/20 0.42
▸ RCOR1 Q9UKL0 1/20 0.40
▸ HCAR2 Q8TDS4 1/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL434672 0.90 KDM4E (0.50) KDM1AKDM1BKDM4EGAAADRA1D
SCHEMBL316350 0.90 KDM4E (0.55) KDM1AKDM1BKDM4EGAAADRA1D
SCHEMBL22321328 0.89 KDM4E (0.46) KDM1AKDM1BKDM4EGAAADRA1D
SCHEMBL11920714 0.89 KDM1A (0.44) KDM1AKDM1BKDM4EGAAADRA1D
SCHEMBL22321329 0.89 KDM4E (0.46) KDM1AKDM1BKDM4EGAAADRA1D
SCHEMBL10091165 0.89 KDM1A (0.44) KDM1AKDM1BKDM4EGAAADRA1D
Ammonia Solution, Strong SCHEMBL17982788 0.88 KDM4E (0.48) KDM1AKDM1BKDM4EGAAADRA1D
SCHEMBL29436912 0.88 KDM4E (0.53) KDM1AKDM1BKDM4EGAAADRA1D
SCHEMBL128052 0.88 KDM4E (0.53) KDM1AKDM1BKDM4EGAAADRA1D
SCHEMBL17068945 0.88 KDM4E (0.53) KDM1AKDM1BKDM4EGAAADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311907-B Preparation method of high-purity prasugrel 吉瑞工厂 2022-09-13 — — CN claimed
EP-3363788-A1 CANNABINOID RECEPTOR MODULATORS Arena Pharmaceuticals, Inc. (US) 2018-08-22 — — EP claimed
CN-108218889-A A kind of preparation method of high-purity prasugrel 董丹丹 2018-06-29 — — CN claimed
US-20160060267-A1 PYRAZOLO COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2016-03-03 — — US claimed
EP-2970307-A1 PYRAZOLO COMPOUNDS AND USES THEREOF Genentech, Inc. (US) 2016-01-20 — — EP claimed
WO-2014139326-A1 PYRAZOLO COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2014-09-18 — — WO claimed
US-20130165412-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2013-06-27 — — US claimed
EP-2601200-A2 PREPARATION OF PRASUGREL HYDROCHLORIDE Dr. Reddy's Laboratories Ltd. (IN) 2013-06-12 — — EP claimed
US-20120214766-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2012-08-23 — — US claimed
US-20120202066-A1 Processes For Preparing Prasugrel And Pharmaceutically Acceptable Salts Thereof MSN LABORATORIES LIMITED (IN) 2012-08-09 — — US claimed
EP-2470508-A1 CANNABINOID RECEPTOR MODULATORS Arena Pharmaceuticals, Inc. (US) 2012-07-04 — — EP claimed
WO-2012018791-A2 PREPARATION OF PRASUGREL HYDROCHLORIDE DR. REDDY'S LABORATORIES LTD. (IN) 2012-02-09 — — WO claimed
WO-2011025541-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. (US) 2011-03-03 — — WO claimed
US-11771695-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2023-10-03 — — US disclosed
US-11746091-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2023-09-05 — — US disclosed
EP-3798217-B1 PIPERIDINE CXCR7 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2023-02-22 — — EP disclosed
WO-2009122440-A1 PROCESS FOR THE PREPARATION OF 2-ACETOXY-5-(α -CYCLOPRPYLCARBONYL -2-FLUOROBENZYL)-4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE TORRENT PHARMACEUTICALS LTD. (IN) 2009-10-08 — — WO disclosed
EP-2057115-A1 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES Array Biopharma, Inc. (US) 2009-05-13 — — EP disclosed
EP-1174412-B1 POLYMERIZABLE COMPOSITION SHOWING LIQUID-CRYSTAL PHASE AND OPTICALLY ANISOTROPIC FILM PREPARED FROM SAID COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2008-12-17 — — EP disclosed
WO-2008024746-A1 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES ARRAY BIOPHARMA, INC. (US) 2008-02-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120214766-A1 CANNABINOID RECEPTOR MODULATORS CNR1, CNR2, TRPV1 KDM1A 2127/4885KDM1B 2226/4885KDM4E 3533/4885
US-20160060267-A1 PYRAZOLO COMPOUNDS AND USES THEREOF KDM5A, KDM5C, KDM5B KDM1A 6/4885KDM1B 4/4885KDM4E 12/4885
US-11746091-B2 Cannabinoid receptor modulators CNR1, CNR2, TRPV1 KDM1A 2127/4885KDM1B 2226/4885KDM4E 3533/4885
US-11771695-B2 Cannabinoid receptor modulators CNR2, CNR1, OPRL1 KDM1A 3003/4885KDM1B 3352/4885KDM4E 3391/4885
US-20130165412-A1 CANNABINOID RECEPTOR MODULATORS CNR1, CNR2, TRPV1 KDM1A 2127/4885KDM1B 2226/4885KDM4E 3533/4885
US-20120202066-A1 Processes For Preparing Prasugrel And Pharmaceutically Acceptable Salts Thereof SF1, PFKP, CYP2F1 KDM1A 3205/4885KDM1B 4428/4885KDM4E 3711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.