Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.59 |
| ▸ | CA2 | P00918 | 10/20 | 0.59 |
| ▸ | CA9 | Q16790 | 8/20 | 0.59 |
| ▸ | CA4 | P22748 | 7/20 | 0.59 |
| ▸ | CA12 | O43570 | 5/20 | 0.59 |
| ▸ | CA3 | P07451 | 5/20 | 0.59 |
| ▸ | CA6 | P23280 | 5/20 | 0.59 |
| ▸ | CA5A | P35218 | 5/20 | 0.59 |
| ▸ | CA7 | P43166 | 5/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 5/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CA11 | O75493 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21558844 | 0.82 | CA1 (0.68) | CA1CA2CA9CA4CA12 | |
| SCHEMBL11560868 | 0.82 | CA1 (0.49) | CA1CA2CA9CA4CA12 | |
| SCHEMBL20369004 | 0.81 | CA1 (0.56) | CA1CA2CA9CA4CA12 | |
| SCHEMBL20097478 | 0.77 | CA1 (0.47) | CA1CA2CA9CA4CA12 | |
| SCHEMBL11930741 | 0.75 | CA1 (0.76) | CA1CA2CA9CA4CA12 | |
| SCHEMBL10797173 | 0.75 | CA1 (1.00) | CA1CA2CA9CA4CA12 | |
| SCHEMBL18651260 | 0.75 | CA1 (0.49) | CA1CA2CA9CA4CA12 | |
| SCHEMBL18651390 | 0.74 | CA1 (0.51) | CA1CA2CA9CA4CA12 | |
| SCHEMBL11391297 | 0.74 | CA1 (0.64) | CA1CA2CA9CA4CA12 | |
| Hydrochloric Acid SCHEMBL10464123 | 0.74 | CA1 (0.70) | CA1CA2CA9CA4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9956302-B2 | Compounds and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2018-05-01 | — | — | US | disclosed |