Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.47 |
| ▸ | CA2 | P00918 | 9/20 | 0.47 |
| ▸ | CA9 | Q16790 | 7/20 | 0.47 |
| ▸ | CA4 | P22748 | 6/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA3 | P07451 | 3/20 | 0.47 |
| ▸ | CA6 | P23280 | 3/20 | 0.47 |
| ▸ | CA5A | P35218 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CA11 | O75493 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18651380 | 0.81 | CA1 (0.40) | CA1CA2CA9CA4CA12 | |
| SCHEMBL18651377 | 0.80 | CA1 (0.41) | CA1CA2CA9CA4CA12 | |
| SCHEMBL18651266 | 0.78 | CA1 (0.41) | CA1CA2CA9CA4CA12 | |
| SCHEMBL18651384 | 0.77 | CA1 (0.43) | CA1CA2CA9CA4CA12 | |
| SCHEMBL20097477 | 0.77 | CA1 (0.59) | CA1CA2CA9CA4CA12 | |
| SCHEMBL18651267 | 0.76 | KMT2A (0.40) | CA1CA2CA9CA4CA12 | |
| SCHEMBL21558844 | 0.72 | CA1 (0.68) | CA1CA2CA9CA4CA12 | |
| SCHEMBL11391297 | 0.70 | CA1 (0.64) | CA1CA2CA9CA4CA12 | |
| SCHEMBL19937285 | 0.69 | CA1 (0.59) | CA1CA2CA9CA4CA12 | |
| SCHEMBL11930741 | 0.69 | CA1 (0.76) | CA1CA2CA9CA4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9956302-B2 | Compounds and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2018-05-01 | — | — | US | disclosed |