Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.60 |
| ▸ | PTGFR | P43088 | 14/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20097487 | 0.94 | PTGFR (0.55) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| SCHEMBL20097490 | 0.89 | PTGFR (0.60) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| SCHEMBL18651339 | 0.88 | SLCO2A1 (0.67) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| SCHEMBL18651338 | 0.85 | SLCO2A1 (0.67) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| SCHEMBL19845837 | 0.84 | SLCO2A1 (0.70) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| SCHEMBL19931399 | 0.84 | SLCO2A1 (0.65) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| SCHEMBL20097486 | 0.83 | PDE4D (0.54) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| SCHEMBL18651344 | 0.82 | PTGFR (0.60) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| SCHEMBL18656729 | 0.82 | SLCO2A1 (0.78) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| SCHEMBL19845841 | 0.81 | PTGFR (0.59) | SLCO2A1PTGFRKDM4EMEN1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9956302-B2 | Compounds and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2018-05-01 | — | — | US | disclosed |