Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20097485 | 0.94 | SLCO2A1 (0.60) | PTGFRKDM4EABCB11MEN1MAPT | |
| SCHEMBL20097490 | 0.90 | PTGFR (0.60) | PTGFRKDM4EABCB11MEN1MAPT | |
| SCHEMBL18651344 | 0.89 | PTGFR (0.60) | PTGFRKDM4EABCB11MEN1MAPT | |
| SCHEMBL19931413 | 0.85 | PTGFR (0.59) | PTGFRKDM4EABCB11MEN1MAPT | |
| SCHEMBL20097486 | 0.84 | PDE4D (0.54) | PTGFRKDM4EABCB11MEN1MAPT | |
| SCHEMBL19845841 | 0.82 | PTGFR (0.59) | PTGFRKDM4EABCB11MEN1MAPT | |
| SCHEMBL18656682 | 0.82 | PTGFR (0.69) | PTGFRKDM4EABCB11MEN1MAPT | |
| SCHEMBL18651339 | 0.82 | SLCO2A1 (0.67) | PTGFRKDM4EABCB11MEN1MAPT | |
| SCHEMBL18651349 | 0.82 | PTGFR (0.72) | PTGFRKDM4EABCB11MEN1MAPT | |
| SCHEMBL19845843 | 0.81 | PTGFR (0.62) | PTGFRKDM4EABCB11MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9956302-B2 | Compounds and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2018-05-01 | — | — | US | disclosed |