Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | YWHAG | P61981 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LGMN | Q99538 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78016 | 0.88 | MAPT (0.58) | PRKDCMAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL23059699 | 0.86 | MAPT (0.56) | PRKDCMAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL18669179 | 0.86 | MAPT (0.55) | MAPTSMN1; SMN2GAAALDH1A1ALOX15 | |
| SCHEMBL21549442 | 0.84 | SMN1; SMN2 (0.50) | PRKDCMAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL17113124 | 0.84 | GAA (0.51) | PRKDCMAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL1237577 | 0.82 | ALDH1A1 (0.61) | PRKDCMAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL4100817 | 0.81 | GAA (0.53) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL24227047 | 0.81 | KDM4E (0.43) | MAPTALOX15KDM4EMEN1THRB | |
| SCHEMBL18412927 | 0.79 | ALDH1A1 (0.55) | PRKDCMAPTSMN1; SMN2ALDH1A1ALOX15 | |
| SCHEMBL20097525 | 0.79 | PRKDC (0.68) | PRKDCMAPTSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957281-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2018-05-01 | — | — | US | disclosed |