Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.50 |
| ▸ | LPAR4 | Q99677 | 4/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.50 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | VEGFA | P15692 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136705 | 1.00 | KDM4E (0.52) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL9814680 | 0.86 | ALDH1A1 (0.61) | LMNALPAR1ENPP2LPAR2LPAR3 | |
| SCHEMBL7617720 | 0.86 | ALDH1A1 (0.61) | LMNALPAR1ENPP2LPAR2LPAR3 | |
| SCHEMBL9466046 | 0.85 | KMT2A (0.41) | KDM4EKMT2ALMNAMAPT | |
| SCHEMBL9466040 | 0.85 | KMT2A (0.41) | KDM4EKMT2ALMNAMAPT | |
| SCHEMBL14569472 | 0.84 | CYP3A4 (0.43) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL5510211 | 0.84 | MAPT (0.41) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL5071377 | 0.82 | PLA2G2C (0.45) | KDM4ELMNAMAPT | |
| SCHEMBL9625505 | 0.82 | PLA2G2C (0.45) | KDM4ELMNAMAPT | |
| SCHEMBL9625787 | 0.82 | PLA2G2C (0.45) | KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957546-B2 | Vivo detection of phospholipase activation | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-05-01 | — | — | US | disclosed |