SCHEMBL20097776

SCHEMBL20097776

O=C(O)c1cc2cc(NSc3ccc(Cl)cc3)ccc2s1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.44
HDAC1 Q13547 7/20 0.44
GPR35 Q9HC97 1/20 0.41
PRSS12 P56730 1/20 0.39
TBXAS1 P24557 1/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
CLK1 P49759 1/20 0.38
CLK2 P49760 1/20 0.38
DYRK1A Q13627 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
CHRNA7 P36544 2/20 0.38
HTR3A P46098 2/20 0.38
CCNC P24863 1/20 0.38
CDK8 P49336 1/20 0.38
RPA1 P27694 1/20 0.36
NOTUM Q6P988 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20097867 0.87 MEN1 (0.51) BCL2L1HDAC1GPR35TBXAS1MEN1
SCHEMBL11956687 0.79 MEN1 (0.51) HDAC1MEN1MAPTKMT2ACLK1
SCHEMBL29742302 0.78 BCL2L1 (0.59) BCL2L1GPR35TBXAS1CLK1CLK2
SCHEMBL740202 0.78 BCL2L1 (0.59) BCL2L1GPR35TBXAS1CLK1CLK2
SCHEMBL19880960 0.77 BCL2L1 (0.51) BCL2L1HDAC1GPR35TBXAS1MEN1
SCHEMBL15697492 0.77 MEN1 (0.64) HDAC1PRSS12MEN1MAPTKMT2A
SCHEMBL3498018 0.76 BCL2L1 (0.53) BCL2L1GPR35TBXAS1CLK1DYRK1A
SCHEMBL19880950 0.74 BCL2L1 (0.47) BCL2L1HDAC1GPR35TBXAS1MEN1
SCHEMBL7540620 0.72 BCL2L1 (0.56) BCL2L1HDAC1GPR35TBXAS1CLK1
SCHEMBL17135415 0.72 HDAC1 (0.55) BCL2L1HDAC1GPR35TBXAS1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed