SCHEMBL19880950

SCHEMBL19880950

O=C(O)c1cc2cc(NSC(F)(F)F)ccc2s1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.47
HDAC1 Q13547 8/20 0.47
PTPN2 P17706 2/20 0.46
GPR35 Q9HC97 2/20 0.44
TBXAS1 P24557 2/20 0.41
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
CLK1 P49759 2/20 0.38
DYRK1A Q13627 2/20 0.38
DYRK1B Q9Y463 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19880958 0.88 MEN1 (0.54) HDAC1PTPN2MEN1MAPTKMT2A
SCHEMBL19880960 0.81 BCL2L1 (0.51) BCL2L1HDAC1PTPN2GPR35TBXAS1
SCHEMBL15697503 0.80 HDAC1 (0.51) BCL2L1HDAC1PTPN2GPR35TBXAS1
SCHEMBL15697524 0.78 PPARA (0.53) BCL2L1HDAC1PTPN2GPR35TBXAS1
SCHEMBL15697602 0.78 GPR35 (0.51) BCL2L1HDAC1PTPN2GPR35TBXAS1
SCHEMBL17135415 0.75 HDAC1 (0.55) BCL2L1HDAC1GPR35TBXAS1MEN1
SCHEMBL153428 0.74 BCL2L1 (0.54) BCL2L1PTPN2GPR35TBXAS1CLK1
SCHEMBL20097867 0.74 MEN1 (0.51) BCL2L1HDAC1GPR35TBXAS1MEN1
SCHEMBL20097776 0.74 BCL2L1 (0.44) BCL2L1HDAC1GPR35TBXAS1MEN1
SCHEMBL15697598 0.72 MEN1 (0.55) BCL2L1HDAC1GPR35TBXAS1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 US disclosed