SCHEMBL20098007

SCHEMBL20098007

CCc1c(C(=O)c2ccc(Sc3ccc(/C(C)=N/OC(C)=O)cc3)cc2)oc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.41
SLC22A12 Q96S37 1/20 0.41
EYA3 Q99504 1/20 0.41
ALDH1A1 P00352 5/20 0.41
NPSR1 Q6W5P4 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 6/20 0.40
SMN1; SMN2 Q16637 5/20 0.40
KDM4E B2RXH2 3/20 0.40
HPGD P15428 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
ALOX12 P18054 1/20 0.40
HTT P42858 1/20 0.40
NPC1 O15118 4/20 0.39
RAB9A P51151 3/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
CYP2C19 P33261 1/20 0.39
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16581260 0.89 CYP2C9 (0.39) CYP2C9SLC22A12EYA3ALDH1A1NPSR1
SCHEMBL20098009 0.86 NPC1 (0.44) ALDH1A1L3MBTL1MAPTSMN1; SMN2KDM4E
SCHEMBL16581244 0.86 NPC1 (0.44) ALDH1A1L3MBTL1MAPTSMN1; SMN2KDM4E
SCHEMBL16581091 0.85 CYP2C9 (0.37) CYP2C9SLC22A12EYA3ALDH1A1NPSR1
SCHEMBL20098017 0.84 PTPN1 (0.51) ALDH1A1MAPTSMN1; SMN2KDM4EHPGD
SCHEMBL16581049 0.83 PTPN1 (0.55) ALDH1A1L3MBTL1MAPTSMN1; SMN2KDM4E
SCHEMBL17945819 0.76 KCNH2 (0.41) CYP2C9ALDH1A1NPSR1L3MBTL1MAPT
SCHEMBL17945978 0.76 NPC1 (0.38) SLC22A12EYA3ALDH1A1L3MBTL1MAPT
SCHEMBL20412680 0.75 PTPN1 (0.50) ALDH1A1L3MBTL1MAPTSMN1; SMN2KDM4E
SCHEMBL11830538 0.75 EYA3 (0.64) CYP2C9SLC22A12EYA3ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957258-B2 Oxime ester photoinitiators BASF SE (DE) 2018-05-01 US disclosed