Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.57 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18658742 | 0.91 | SLC6A2 (0.46) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26024845 | 0.88 | CFTR (0.49) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24611172 | 0.85 | CFTR (0.46) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21770565 | 0.85 | CFTR (0.47) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24919838 | 0.85 | CFTR (0.47) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23689571 | 0.85 | CFTR (0.47) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11337414 | 0.85 | CFTR (0.47) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25147575 | 0.84 | CFTR (0.43) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18400269 | 0.83 | KCNA5 (0.45) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20465414 | 0.83 | KCNA5 (0.45) | CFTRGOPCSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787811-B2 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-10-17 | — | — | US | disclosed |
| US-11180506-B2 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2021-11-23 | — | — | US | disclosed |
| US-9957281-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2018-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180506-B2 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | CFTR 504/4885GOPC 2275/4885SLC6A2 4869/4885 |
| US-11787811-B2 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | CFTR 504/4885GOPC 2275/4885SLC6A2 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.