Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.40 |
| ▸ | STK3 | Q13188 | 2/20 | 0.40 |
| ▸ | STK26 | Q9P289 | 1/20 | 0.40 |
| ▸ | CBLB | Q13191 | 6/20 | 0.38 |
| ▸ | CCKAR | P32238 | 2/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20098616 | 1.00 | LRRK2 (0.40) | LRRK2STK3STK26CBLBCCKAR | |
| SCHEMBL20098482 | 0.90 | CBLB (0.46) | LRRK2STK3STK26CBLBCCKAR | |
| SCHEMBL20098618 | 0.90 | CBLB (0.46) | LRRK2STK3STK26CBLBCCKAR | |
| SCHEMBL21117375 | 0.82 | LRRK2 (0.43) | LRRK2STK3CBLBCCKARCCKBR | |
| SCHEMBL20098124 | 0.81 | CCKBR (0.44) | LRRK2CBLBCCKARCCKBR | |
| SCHEMBL20098252 | 0.81 | CCKBR (0.44) | LRRK2CBLBCCKARCCKBR | |
| SCHEMBL20098695 | 0.81 | BRD4 (0.35) | CBLBCREBBP | |
| SCHEMBL20098430 | 0.78 | CBLB (0.45) | CBLBCCKARCCKBR | |
| SCHEMBL20098442 | 0.78 | CBLB (0.45) | CBLBCCKARCCKBR | |
| SCHEMBL20098735 | 0.78 | CCKAR (0.35) | CCKARCCKBRCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957281-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2018-05-01 | — | — | US | disclosed |