⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29913009 | 1.00 | — | — | |
| Methane SCHEMBL14630339 | 0.97 | — | — | |
| SCHEMBL1256526 | 0.82 | PIK3CD (0.37) | — | |
| SCHEMBL1024624 | 0.75 | — | — | |
| SCHEMBL29985108 | 0.75 | — | — | |
| SCHEMBL103808 | 0.75 | — | — | |
| SCHEMBL11528959 | 0.71 | MAPKAPK2 (0.32) | — | |
| SCHEMBL12501047 | 0.71 | LMNA (0.48) | — | |
| SCHEMBL28173312 | 0.68 | MAP4K4 (0.48) | — | |
| Pyrazine SCHEMBL8836982 | 0.67 | HSP90AA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119009136-A | Pyrazinyl eutectic electrolyte with wide electrochemical stability window, and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-11-22 | — | — | CN | claimed |
| CN-114989175-B | Imidazopyrazine compound and application thereof | 广东晨康生物科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-117050085-A | Aryl substituted 8-amino imidazo pyrazine compound, and preparation method and application thereof | 广西大学 | 2023-11-14 | — | — | CN | claimed |
| CN-114478523-B | Organic luminescent material and preparation method and application thereof | 西安凯翔光电科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-114989175-A | Imidazopyrazine-containing compound and application thereof | 佛山市晨康生物科技有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-114478523-A | Organic luminescent material and preparation method and application thereof | 西安凯翔光电科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-112654624-A | Coelenterazine compound intermediate and synthetic method of coelenterazine compound | 深圳华大智造极创科技有限公司 | 2021-04-13 | — | — | CN | claimed |
| WO-2020061826-A1 | INTERMEDIATE OF COELENTERAZINE COMPOUND AND METHOD FOR SYNTHESIZING COELENTERAZINE COMPOUND | 深圳华大智造极创科技有限公司 | 2020-04-02 | — | — | WO | claimed |
| CN-108163931-A | The graphite electrode modified based on CeO-ZrO-NiO and pyrazine | 光合强化（北京）生物科技有限公司 | 2018-06-15 | — | — | CN | claimed |
| CN-107855111-A | Caesium sorbing material based on sodium modified zeolite and preparation method thereof | 北京源清益壤环保科技有限公司 | 2018-03-30 | — | — | CN | claimed |
| CN-107497403-A | For solidifying the diatomite adsorbing material of mercury in river bottom mud | 北京清水润土环保科技有限公司 | 2017-12-22 | — | — | CN | claimed |
| WO-2012168733-A1 | SUBSTITUTED 8 - AMINO - IMIDAZO [1, 2-A] PYRAZINES AS ANTIBACTERIAL AGENTS | UCL BUSINESS PLC (GB) | 2012-12-13 | — | — | WO | claimed |
| CN-101817823-B | Preparation method of 4,7-diazaindole and 5-site substitute thereof | SHANGHAI BEPHARM SCIENCE & TECHNOLOGY CO LTD | 2012-09-12 | — | — | CN | claimed |
| EP-2336315-A2 | Enzymatic encoding methods for efficient synthesis of large libraries | Nuevolution A/S (DK) | 2011-06-22 | — | — | EP | claimed |
| CN-101817823-A | Preparation method of 4,7-diazaindole and 5-site substitute thereof | SHANGHAI BEPHARM SCIENCE & TECHNOLOGY CO LTD | 2010-09-01 | — | — | CN | claimed |
| EP-4743078-A2 | APOL1 INHIBITORS AND METHODS OF USE | Maze Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| CN-117062813-B | Polycyclic compound and application thereof | 四川汇宇制药股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| US-4233301-A | ADRENERGIC BLOCKING AGENTS | MERCK & CO., INC. (US) | 1980-11-11 | — | — | US | disclosed |
| US-4166851-A | ADRENERGIC BLOCKING AGENTS | MERCK & CO., INC. (US) | 1979-09-04 | — | — | US | disclosed |
| US-4123613-A | Substituted pyrazines as inhibitors of platelet aggregation | SOCIETA FARMACEUTICI ITALIA S.P.A. (IT) | 1978-10-31 | — | — | US | disclosed |