Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20099566 | 0.95 | CHRNB4 (0.34) | FDPSCYP2D6CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL18353420 | 0.81 | FDPS (0.42) | FDPSCYP2D6CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL18353417 | 0.81 | FDPS (0.42) | FDPSCYP2D6CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL9120471 | 0.81 | FDPS (0.42) | FDPSCYP2D6CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL22908385 | 0.81 | CYP2D6 (0.41) | FDPSCYP2D6CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL4148616 | 0.81 | CYP2D6 (0.41) | FDPSCYP2D6CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL18353418 | 0.76 | FDPS (0.36) | FDPSCYP2D6CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL20099573 | 0.76 | FDPS (0.36) | FDPSCYP2D6CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL18353686 | 0.76 | FDPS (0.36) | FDPSCYP2D6CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL25566390 | 0.75 | CYP2D6 (0.41) | FDPSCYP2D6CYP1A2KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957267-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2018-05-01 | — | — | US | disclosed |