Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | KIF11 | P52732 | 3/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100122 | 0.98 | NPC1 (0.60) | NPC1RAB9AKIF11XDHMAPT | |
| SCHEMBL19901704 | 0.98 | NPC1 (0.60) | NPC1RAB9AKIF11XDHMAPT | |
| SCHEMBL27375500 | 0.96 | NPC1 (0.62) | NPC1RAB9AKIF11XDHMAPT | |
| SCHEMBL15281174 | 0.91 | TSHR (0.54) | NPC1RAB9AKIF11XDHMAPT | |
| SCHEMBL16769401 | 0.91 | TSHR (0.54) | NPC1RAB9AKIF11XDHMAPT | |
| SCHEMBL19400301 | 0.89 | NPC1 (0.51) | NPC1RAB9AKIF11XDHMAPT | |
| SCHEMBL4125159 | 0.89 | NPC1 (0.69) | NPC1RAB9AKIF11XDHMAPT | |
| SCHEMBL13871684 | 0.89 | NPC1 (0.69) | NPC1RAB9AKIF11XDHMAPT | |
| SCHEMBL16769408 | 0.88 | NPC1 (0.46) | NPC1RAB9AKIF11XDHMAPT | |
| SCHEMBL16921346 | 0.88 | NPC1 (0.46) | NPC1RAB9AKIF11XDHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180123056-A1 | LIGHT EMITTING DEVICE AND COMPOSITION USED FOR THIS LIGHT EMITTING DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180123056-A1 | LIGHT EMITTING DEVICE AND COMPOSITION USED FOR THIS LIGHT EMITTING DEVICE | CHRM1, CRY1, L1CAM | NPC1 3836/4885RAB9A 2799/4885KIF11 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.