Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26833769 | 0.84 | MEN1 (0.51) | MEN1KMT2AHTTGAASCD | |
| SCHEMBL31342915 | 0.84 | MEN1 (0.51) | MEN1KMT2AHTTGAASCD | |
| SCHEMBL13734562 | 0.83 | KMT2A (0.40) | MEN1KMT2AHTTGAASCD | |
| SCHEMBL16036416 | 0.80 | MEN1 (0.45) | MEN1KMT2AHTTGAASCD | |
| SCHEMBL13734986 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNA | |
| SCHEMBL24477372 | 0.78 | KMT2A (0.46) | MEN1KMT2AHTTGAASCD | |
| SCHEMBL15770459 | 0.78 | MEN1 (0.46) | MEN1KMT2AHTTGAASCD | |
| Hydrochloric Acid SCHEMBL4091933 | 0.77 | IKBKB (0.48) | MEN1KMT2ASCD | |
| SCHEMBL25292960 | 0.76 | IKBKB (0.40) | MEN1KMT2ASCD | |
| SCHEMBL31302387 | 0.75 | MEN1 (0.67) | MEN1KMT2AHTTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018079628-A1 | PYRROLE DERIVATIVE WITH FUSED RING AND PHARMACEUTICAL USE THEREOF | 大日本住友製薬株式会社 | 2018-05-03 | — | — | WO | disclosed |