SCHEMBL20100293

SCHEMBL20100293

C=C(C)C(=O)OCC(=O)N(C(=O)C(F)(F)F)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
THRB P10828 1/20 0.37
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20100366 0.88
SCHEMBL20100332 0.75 CHRM2 (0.33)
SCHEMBL20100321 0.74 TSHR (0.33) TSHRALDH1A1
SCHEMBL21699667 0.70 CHRM2 (0.38)
SCHEMBL27360000 0.69 THRB (0.48) TSHRTHRBALDH1A1
SCHEMBL10024378 0.69 TSHR (0.57) TSHRTHRBALDH1A1
SCHEMBL11887999 0.68 THRB (0.44) TSHRTHRBALDH1A1
SCHEMBL2608065 0.67 TSHR (0.46) TSHRTHRBALDH1A1
SCHEMBL21714540 0.66 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL18031807 0.66 TSHR (0.48) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed