SCHEMBL20100318

SCHEMBL20100318

C=C(C)C(=O)OC(C)C(=O)NC(=O)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20100310 0.87
SCHEMBL20100290 0.85 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL20100308 0.84 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL20100304 0.80 TSHR (0.35) ALDH1A1TSHR
SCHEMBL20100339 0.78 CYP1A2 (0.30)
SCHEMBL20100439 0.74 NPC1 (0.41)
SCHEMBL20100337 0.73 KMT2A (0.32)
SCHEMBL6308116 0.73 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL20100338 0.73 S1PR1 (0.30)
SCHEMBL20100305 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed