SCHEMBL20100416

SCHEMBL20100416

C=CC(=O)OC(CC(C)C)CC(C)(O)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20103329 0.87 TSHR (0.39) TSHR
SCHEMBL28880700 0.82 TSHR (0.35) TSHR
SCHEMBL12791912 0.81 TSHR (0.38) TSHR
SCHEMBL440018 0.79 TSHR (0.38) TSHR
SCHEMBL27477306 0.79 TSHR (0.52) TSHR
SCHEMBL23963405 0.78 TSHR (0.42) TSHR
SCHEMBL16591713 0.78
SCHEMBL13422188 0.77
SCHEMBL440065 0.77
SCHEMBL13239958 0.74 TSHR (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118968-A1 TOPCOAT COMPOSITIONS CONTAINING FLUORINATED THERMAL ACID GENERATORS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-05-03 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed